Professor Darren Hargrave specialises in paediatric neuro-oncology and the development of new anti-cancer drugs for children and adolescents. He trained in the UK and was the inaugural neuro-oncology clinical fellow at the Hospital for Sick Children in Toronto. Upon returning to the UK he was a Consultant Paediatric Oncologist at the Royal Marsden for 10 years before moving to Great Ormond Street Children’s Hospital in 2011 where he leads the experimental therapeutics programme and is a Professor in Paediatric Neuro-oncology at the Institute of Child Health (University College London). He is the current Chair of the Children’s Novel Agents Subgroup of the UK NCRI, Chair Elect of the SIOP-E Brain Tumour Group where he previously Chaired of the High-Grade Glioma working group. He is a member of the Guy’s Complex NF1 clinic and has an interest in NF related tumours. He sits on the ITCC Clinical Trials Committee and is a Chief Investigator of over 15 completed, on-going and planned clinical trials in paediatric cancer. His research interests include: the biology of childhood brain tumours, the use of innovative imaging techniques in childhood cancer and drug development of targeted therapies in childhood and adolescent oncology.